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Background: The Losartan Intervention For Endpoint reduction (LIFE) study was a randomized, doubleblind trial that compared the effects of
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Although the clinical trials will ultimately decide the safety and efficacy of losartan treatment for patients with Marfan syndrome, Dietz said the
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This multicenter trial evaluated whether progression of nephropathy and to receive losartan, enalapril or placebo were followed for five years.
Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE). Lancet 1997; 349:747-52.
In contrast to other more recent losartan trials (LIFE, RENAAL) [14,15], ELITE II used only a moderate dose of losartan: 50 mg daily. Consequently, HEAAL was
Before the start of that clinical trial, physicians at Johns Hopkins felt compelled to first try losartan in a small group of children, with severe Marfan syndrome,
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trial, evaluating the effects of losartan and captopril on mortality and morbidity in a larger number of patients with heart failure, is in progress. Lancet 1997; 349:
The AMADEO trial was conducted to determine whether pharmacological differences between telmisartan and losartan would translate into
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AVAPRO demonstrated once-daily superior DBP-reducing power vs losartan at Superiority demonstrated in another well-controlled DBP reduction trial*
The main objective of this trial is to assess whether losartan treatment leads to a clinically relevant decrease of aortic dilatation in adult patients
The antihypertensive effects of losartan were demonstrated principally in 4 placebo-controlled, 6- to. 12-week trials of dosages from 10 to 150 mg per day in
Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial
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Continuum of Renoprotection with Losartan at All Stages of Type 2 Diabetic Nephropathy: A Post Hoc Analysis of the RENAAL Trial Results
In Reply: Drs Fruhwald and Pieske suggest that losartan should not be used in HF. Randomized controlled trials have compared losartan,
The aim of this trial was to evaluate the potential renoprotective capacity with losartan (100 mg daily) and optimal treatment for hypertension.
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A randomized trial comparing losartan with amlodipine as initial therapy for hypertension in the early post-transplant period (2006). Formica, Richard N.
Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE). Auteur(s) / Author(s)
The efficacy and safety of losartan and valsartan were evaluated in a multicenter, double-blind, randomized trial in patients with mild to
This is a 6 year randomised trial in IgA nephritis comparing high dose ARB ( Losartan 200 mg/day) with normal dose ARB (Losartan 100 mg/day), normal dose
Losartan Trial Investigators. PubMed Journal article. Search PubMed by keyword , journal, author or by EBM filters diagnosis, treatment, prognosis or etiology.
Cardiovascular morbidity and mortality in the Losartan Intervention For End point reduction in hypertension study (LIFE): a randomized trial against atenolol.
This assumed an annual mortality rate of 8.1% (candesartan group in the CHARM-Overall trial18) and 11.7% (losartan group in the ELITE II
Losartan Potassium And Ramipril Combination losartan 50mg prospective randomized open-label clinical trial comparing the effects of losartan
Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial—the Losartan Heart Failure Survival Study
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Thus, although currently there is now ample evidence, including from this recent aliskiren and losartan trial, that dual blockade may be
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Lay Summary, This is a randomized, controlled trial to determine whether Losartan is effective at slowing down, halting or reversing liver fibrosis in patients with
The RENAAL (Reduction of End Points in Type 2 Diabetes With the Angiotensin II Antagonist Losartan) trial was a randomized double-blind study comparing the
Telmisartan, but not losartan, significantly (p < 0.05) reduced free plasma glucose , .. and in combination with Ramipril Global Endpoint Trial (ONTARGET) [39].
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Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomized trial-the Losartan Heart Failure Survival Study
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morbidity and mortality in the Losartan For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet 2002;359:995-1003
The Evaluation of Losartan in the Elderly (ELITE). Trial'1^ is the first relatively long term (48 weeks) trial to compare an angiotensin converting enzyme
A randomised controlled trial of losartan as an anti-fibrotic agent in non- alcoholic steatohepatitis. Project Ref: 08-43-15. Cost: £941463. Lead Applicant. &
Cardiovas- cular morbidity and mortality in the Losartan Inter- vention for Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol.
Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE). (PMID:9074572). Abstract
Data on health care resource utilization were collected as part of the trial. into a cost-effectiveness ratio of USD 4047 per year of life gained for losartan relative
Addition of aliskiren to losartan in patients with hypertension and type 2 diabetes: AVOID trial. Source: N Engl J Med 2008; 358: 2433-2446,
OBJECTIVE -- To evaluate the within-trial effect of losartan and conventional antihypertensive therapy (CT) compared with placebo and CT on
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